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Search Results for " Protein kinase C "

ターゲット

PKC

179

阻害剤

天然化合物

180

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
TP1053L	Protein Kinase C 19-31 acetate	Protein Kinase C 19-31 acetate(121545-65-1 free base),PKC (19-31) acetate	PKC
	Protein Kinase C 19-31 acetate, a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with a serine at position 25 replacing the wild-type alanine, is...		PKC
TP1051L	Protein Kinase C Peptide Substrate acetate	Protein Kinase C Peptide Substrate acetate(120253-69-2 free base)	Others
	Protein Kinase C Peptide Substrate acetate targets specific cell spacers ina manner that is dependent on second messengers and specific adaptor proteins in response to extracellular signals that activate g protein-couple...		Others
TP1503	Protein Kinase C (19-36)	Protein Kinase C 19-36
	Protein Kinase C (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C (PKC), with an IC50 of 0.18 μM.
TP1053	Protein Kinase C (19-31)	Protein Kinase C 19-31,PKC (19-31)
	Protein Kinase C (19-31), a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with a serine at position 25 replacing the wild-type alanine, is used ...
T17148	TPPB		PKC
	TPPB is a kinase C activator of cell-permeable benzolactam-derived protein (Ki: 11.9 nM).		PKC
TP1051	Protein Kinase C Peptide Substrate	PRKCE,Peptide Epsilon,PKCε
	Protein Kinase C Peptide Substrate targets specific cell spacers ina manner that is dependent on second messengers and specific adaptor proteins in response to extracellular signals that activate g protein-coupled recept...
T7648	HA-100		Myosin , PKA , PKC
	HA-100 is an inhibitor of protein kinase		Myosin , PKA , PKC
TP1052	Protein Kinase C (19-31) (TFA)(121545-65-1,free)	PKC (19-31) (TFA),Protein Kinase C (19-31) (TFA)
	Protein Kinase C (19-31) TFA, a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with a serine at position 25 replacing the wild-type alanine, is u...
T7885	Afuresertib hydrochloride		ROCK , Akt , PKC
	Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)		ROCK , Akt , PKC
T1911	Afuresertib	GSK2110183C,GSK2110183	ROCK , Akt , PKC
	Afuresertib (GSK2110183) is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity.		ROCK , Akt , PKC
T14989	CMPD101		ROCK , GRK , PKC
	CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM). Which can be used for the study of heart failure. CMPD101 exhibits less selectively against GRK1, GRK5, ROCK-2 and PKCα with I...		ROCK , GRK , PKC
T14069	A-3 hydrochloride		CaMK , Casein Kinase , PKA , PKC
	A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. A-3 hydrochloride also inhibits PKC and casein kinase I with Ki values of 47 µM and 80 µM, respectiv...		CaMK , Casein Kinase , PKA , PKC
T35407	Ζ-Stat		PKC
	ζ-Stat (NSC37044), a specific and atypical inhibitor of PKC-ζ with an IC50 of 5 μM, demonstrates the ability to inhibit proliferation and induce apoptosis in melanoma cell lines, exhibiting antitumor activity in vitro[1]...		PKC
TP1955L	PKC β pseudosubstrate acetate	Protein kinase C beta pseudosubstrate,PKC beta pseudosubstrate,PKC β pseudosubstrate acetate (172308-76-8 Free base)	PKC
	PKC β pseudosubstrate acetate (PKC β pseudosubstrate acetate (172308-76-8 Free base)) is a selective cell-permeable inhibitor of PKC.		PKC
T76387	Protein kinase C substrate
	Protein Kinase C substrate, a specific substrate of Protein Kinase C, plays a pivotal role in signal transduction by facilitating the detection of protein through its enzyme's catalytic action on specific substrate phosp...
T13314	VTX-27		PKC
	VTX-27 is a selective inhibitor of protein kinase C θ (PKC θ) (Kis: 0.08 nM and 16 nM for PKC θ and PKC δ).		PKC
T76422	Protein Kinase C (661-671)
	Protein Kinase C (661-671), a fragment peptide of the β1 subspecies of Protein Kinase C (PKC), is instrumental in regulating cellular growth and has been implicated in tumor promotion [1] [2].
T76444	Protein Kinase C (660-673)
	Protein Kinase C βII V5 peptide (660-673) (PKC βII (660-673)) exhibits an affinity for binding to RACK1 [1].
T76421	Protein Kinase C β Peptide
	Protein Kinase C (beta) Peptide, a fragment of Protein Kinase Cβ, is associated with hyperglycemia-induced decreases in endothelium-derived nitric oxide. Inhibiting Protein Kinase Cβ forestalls the impairment of endothel...
T76419	Protein Kinase C γ Peptide
	Protein Kinase C (gamma) Peptide, a fragment of Protein Kinase Cγ, plays a role in dominant ataxia by inhibiting the nuclear import of aprataxin, which is associated with recessive ataxia [1].
T2441	TAS-301	TAS 301	PKC
	TAS-301, an inhibitor of smooth muscle cell migration and proliferation, inhibits intimal thickening after balloon injury to rat carotid arteries.		PKC
T7659	Bisindolylmaleimide IV		Others , PKC
	Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)		Others , PKC
T26019	R59949	R-59949,R 59949	Others , PKC
	R59949 is used as a Diacylglycerol kinase (DGK) inhibitor.		Others , PKC
T76388	Protein kinase C α peptide TFA
	Protein Kinase C (alpha) Peptide (TFA) is a PKC-α-associated peptide functioning as a lipid-dependent serine/threonine protein kinase. It plays a pivotal role in regulating several cellular functions such as survival, pr...
T76456	Protein Kinase C (19-35) Peptide
	Protein Kinase C (19-35) Peptide, serving as the PKC pseudosubstrate inhibitor/region, potentially inhibits PKC activity by obstructing the substrate-binding site within its kinase domain, rendering the cytoplasmic form ...
T76008	Protein Kinase C (19-31) (TFA)
	Protein Kinase C (19-31) TFA is a peptide inhibitor derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31), featuring a serine substitution for alanine at position 25. It serves as a substrate pepti...
T8764	PKC-iota inhibitor 1		PKC
	PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)		PKC
T14943	CGP60474		VEGFR , CDK , PKC
	CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC. CGP60474 is also a highly potent anti-endotoxemic agent and inhibits cyclin-dependent kinase (CDK) potently.		VEGFR , CDK , PKC
T17019	TCS 21311	NIBR3049	GSK-3 , JAK , PKC
	TCS 21311 (NIBR3049) is an effective and highly selective inhibitor of JAK3 (IC50: 8 nM). TCS 21311 inhibits PKCα, PKCθ, and GSK3β (IC50s: 13, 68, and 3 nM, respectively). It displays >100-fold selectivity over JAK1, JAK...		GSK-3 , JAK , PKC
TQ0028	EX229	Compound 991,C991	AMPK
	EX229 (C991) is an allosteric activator of AMPK, with Kds of 0.06 μM, 0.06 μM and 0.51 μM for α1β1γ1, α2β1γ1, and α1β2γ1, respectively.		AMPK
T6278	Sotrastaurin	AEB071	PKC
	Sotrastaurin (AEB071) is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).		PKC
T5600	Darovasertib	LXS196	PKC
	Darovasertib (LXS196) is a potent, selective and orally active protein kinase C (PKC) inhibitor(IC50 values of 1.9 nM, 0.4 nM and 3.1 μM for PKCα, PKCθ and GSK3β, respectively).		PKC
T6515	Go6976	Gö 6976	PKC
	Go6976 is a small molecule inhibitor of protein kinase C (PKC). Go6976 has been widely used in biomedical research as a tool to study the role of PKC in various physiological and pathophysiological processes.		PKC
T6313	Go 6983	Goe 6983	PKC
	Go 6983 is a pan-PKC inhibitor targeting PKCα, PKCβ, PKCγ, PKCδ, and PKCζ, exhibiting IC50 values of 7 nM, 7 nM, 6 nM, 10 nM, and 60 nM, respectively.		PKC
T1606	Fasudil	HA-1077,AT877	ROCK , Serine/threonin kinase , Calcium Channel , PKA , PKC , Autophagy
	Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
T1977	Dorsomorphin	Compound C,BML-275	AMPK , Autophagy , TGF-beta/Smad
	Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive. Dorsomorphin inhibits the BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin induces autophagy, and possesses antitumor ...		AMPK , Autophagy , TGF-beta/Smad
T6280	Enzastaurin	LY317615	Apoptosis , PKC , Autophagy
	Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.		Apoptosis , PKC , Autophagy
T7604	Valrubicin	Valstar,AD-32	Antibiotic , PKC
	Valrubicin (AD-32) (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.		Antibiotic , PKC
T10549	Bisindolylmaleimide VIII acetate	Ro 31-7549 acetate,Bis VIII acetate	Apoptosis , PKC
	Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) is a potent and selective PKC inhibitor (IC50: 158 nM for rat brain PKC). It has IC50s of 53, 195, 163, 213, and 175 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, PKC-ε, resp...		Apoptosis , PKC
T11740	Delcasertib	KAI-9803,BMS-875944	PKC
	Delcasertib (KAI-9803) is a potent and selective inhibitor of δ-protein kinase C (δPKC).		PKC
T12148	N-Desmethyltamoxifen hydrochloride		Estrogen Receptor/ERR , Endogenous Metabolite , PKC
	N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.		Estrogen Receptor/ERR , Endogenous Metabolite , PKC
T80509	PKC 20-28,myristoylated	Myristoylated protein kinase C inhibitor 20-28	PKC
	Myristoylated protein kinase C inhibitor 20-28 (PKC 20-28,myristoylated) is a cell-permeable inhibitor of protein kinase C, utilized in cancer research [1].		PKC
T2609	Masitinib	AB1010	Apoptosis , FAK , c-Fms , FGFR , Bcr-Abl , PDGFR , Src , c-Kit , Hck
	Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs. Since its introduction in November 2008 it has been distributed under the commercial name Masivet...
T3060	Fasudil hydrochloride	Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877	ROCK , Serine/threonin kinase , Calcium Channel , HIV Protease , PKA , PKC , Autophagy
	Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
T6588	Mitoxantrone	mitozantrone	Topoisomerase , PKC
	Mitoxantrone (mitozantrone) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisome...		Topoisomerase , PKC
T6146	Dorsomorphin dihydrochloride	BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride	AMPK , Autophagy , TGF-beta/Smad
	Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity on structurally related kinases.		AMPK , Autophagy , TGF-beta/Smad
T4185	Lavendustin C	HDBA,NSC 666251	CaMK , EGFR , Tyrosinase , Src
	lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.		CaMK , EGFR , Tyrosinase , Src
T3689	Ruboxistaurin hydrochloride	Ruboxistaurin,LY333531 HCl,LY 333531 hydrochloride	PKC
	Ruboxistaurin hydrochloride (LY 333531 hydrochloride) is an Isozyme-selective inhibitor of protein kinase C (PKC); competitively and reversibly inhibits PKCβI and PKCβII (IC50 values are 4.7 and 5.9 nM respectively). Sel...		PKC
T8376	PKCβ inhibitor 1	KUN79359	Apoptosis , PKC
	PKCβ inhibitor 1 (KUN79359)(KUN79359) is a potent, selective and ATP-competitive inhibitor of PKC isozymes(IC50s of 21 and 5 nM for human PKCβ1 and PKCβ2, respectively).		Apoptosis , PKC
T6513	Bisindolylmaleimide I	GF109203X,Go 6850	PDGFR , PKC
	Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.		PDGFR , PKC

Compounds

Protein Kinase C 19-31 acetate

TP1053L

Synonym: Protein Kinase C 19-31 acetate(121545-65-1 free base),PKC (19-31) acetate

Target: PKC

Protein Kinase C Peptide Substrate acetate

TP1051L

Synonym: Protein Kinase C Peptide Substrate acetate(120253-69-2 free base)

Target: Others

Protein Kinase C (19-36)

TP1503

Synonym: Protein Kinase C 19-36

Target:

Protein Kinase C (19-31)

TP1053

Synonym: Protein Kinase C 19-31,PKC (19-31)

Protein Kinase C Peptide Substrate

TP1051

Synonym: PRKCE,Peptide Epsilon,PKCε

Target: Myosin, PKA, PKC

Protein Kinase C (19-31) (TFA)(121545-65-1,free)

TP1052

Synonym: PKC (19-31) (TFA),Protein Kinase C (19-31) (TFA)

Target:

Afuresertib hydrochloride

T7885

Synonym:

Target: ROCK, Akt, PKC

Afuresertib

T1911

Synonym: GSK2110183C,GSK2110183

Target: ROCK, Akt, PKC

CMPD101

T14989

Synonym:

Target: ROCK, GRK, PKC

A-3 hydrochloride

T14069

Synonym:

Target: CaMK, Casein Kinase, PKA, PKC

PKC β pseudosubstrate acetate

TP1955L

Synonym: Protein kinase C beta pseudosubstrate,PKC beta pseudosubstrate,PKC β pseudosubstrate acetate (172308-76-8 Free base)

Target: PKC

Protein kinase C substrate

Protein Kinase C (661-671)

T76422

Synonym:

Target:

Protein Kinase C (660-673)

T76444

Synonym:

Target:

Protein Kinase C β Peptide

T76421

Synonym:

Target:

Protein Kinase C γ Peptide

Bisindolylmaleimide IV

Synonym: R-59949,R 59949

Target: Others, PKC

Protein kinase C α peptide TFA

T76388

Synonym:

Target:

Protein Kinase C (19-35) Peptide

T76456

Synonym:

Target:

Protein Kinase C (19-31) (TFA)

Target: VEGFR, CDK, PKC

TCS 21311

T17019

Synonym: NIBR3049

Target: GSK-3, JAK, PKC

EX229

TQ0028

Synonym: Compound 991,C991

Synonym: HA-1077,AT877

Target: ROCK, Serine/threonin kinase, Calcium Channel, PKA, PKC, Autophagy

Dorsomorphin

T1977

Synonym: Compound C,BML-275

Target: AMPK, Autophagy, TGF-beta/Smad

Enzastaurin

T6280

Synonym: LY317615

Target: Apoptosis, PKC, Autophagy

Valrubicin

T7604

Synonym: Valstar,AD-32

Target: Antibiotic, PKC

Bisindolylmaleimide VIII acetate

T10549

Synonym: Ro 31-7549 acetate,Bis VIII acetate

Target: Apoptosis, PKC

Delcasertib

T11740

Synonym: KAI-9803,BMS-875944

Target: PKC

N-Desmethyltamoxifen hydrochloride

T12148

Synonym:

Target: Estrogen Receptor/ERR, Endogenous Metabolite, PKC

PKC 20-28,myristoylated

T80509

Synonym: Myristoylated protein kinase C inhibitor 20-28

Target: Apoptosis, FAK, c-Fms, FGFR, Bcr-Abl, PDGFR, Src, c-Kit, Hck

Fasudil hydrochloride

T3060

Synonym: Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877

Target: ROCK, Serine/threonin kinase, Calcium Channel, HIV Protease, PKA, PKC, Autophagy

Mitoxantrone

T6588

Synonym: mitozantrone

Target: Topoisomerase, PKC

Dorsomorphin dihydrochloride

T6146

Synonym: BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride

Target: AMPK, Autophagy, TGF-beta/Smad

lavendustin C

T4185

Synonym: HDBA,NSC 666251

Target: CaMK, EGFR, Tyrosinase, Src

Ruboxistaurin hydrochloride

T3689

Synonym: Ruboxistaurin,LY333531 HCl,LY 333531 hydrochloride

Target: Apoptosis, PKC

Bisindolylmaleimide I

T6513

Synonym: GF109203X,Go 6850

Target: PDGFR, PKC

カタログ番号	製品名	別名	ターゲット
TN1557	Decursinol angelate		ERK , VEGFR , PKC , JNK
	Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway; it also suppresses invasion an...		ERK , VEGFR , PKC , JNK
T5771	Hypocrellin A		Antibacterial , PKC , Parasite
	Hypocrellin A is PKC inhibitor, has light-induced antitumor,antifungal and antiviral activities, it also exerts immunomodulatory effects on MHC-restricted presentation of antigen.		Antibacterial , PKC , Parasite
T2851	Daphnetin	7,8-Dihydroxycoumarin,Daphnetol	EGFR , PKA , PKC , Parasite , Autophagy
	Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-...		EGFR , PKA , PKC , Parasite , Autophagy
T5S2017	Ingenol	(-)-Ingenol	PKC
	1. Ingenol ((-)-Ingenol) mebutate is an effective treatment for actinic keratosis. 2. Formulating novel derivatives from Ingenol esters may be an innovative approach to develop new lead compounds to reactivate latent HIV...		PKC
T2750	Ginkgolide C	BN-52022	MMP , Sirtuin , Endogenous Metabolite , AMPK
	Ginkgolide C (BN-52022), a natural product, can enhance the cardiac function of rats in the body.		MMP , Sirtuin , Endogenous Metabolite , AMPK
T4S1335	Daphnoretin	Dephnoretin,Thymelol	Influenza Virus , Caspase , PKC
	1. Daphnoretin (Thymelol) has strong antiviral activity, mainly on the later phase of the replication cycle. 2. Daphnoretin has anticancer effects on leukemia, osteosarcoma and uterine cervix cancer cells, might through ...		Influenza Virus , Caspase , PKC
TN1499	Cimiracemoside C	Cimicifugoside M	AMPK
	Cimiracemoside C (Cimicifugoside M) is an active component of Cimicifuga racemosa. It activates AMPK and has the potential activity against diabetes.		AMPK
T6S0052	Chelerythrine	Toddalin,Broussonpapyrine,Cheleritrine	Apoptosis , BCL , PKC , Autophagy
	1. Chelerythrine (Broussonpapyrine) may have antimanic effect . 2. Chelerythrine can inhibit telomerase activity. 3. Chelerythrine is a well-known protein kinase C inhibitor . 4. Chelerythrine has potential antiprolifera...		Apoptosis , BCL , PKC , Autophagy
T3419	Chelerythrine chloride		Apoptosis , BCL , PKC , Autophagy
	Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect to ATP.		Apoptosis , BCL , PKC , Autophagy
T13265	Urolithin B		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
	Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical fruits, and medicinal herbs. Urolithin B inhibits NF-κB activit...		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
TN1299	Desmethylglycitein	6,7,4'-Trihydroxyisoflavone	PI3K , CDK , PKC
	Desmethylglycitein (6,7,4'-Trihydroxyisoflavone) , is a novel inhibitor of PKCα in suppressing solar UV-induced matrix metalloproteinase 1, which has antioxidant, and anti-cancer activities.		PI3K , CDK , PKC
T5552	Methyl cinnamate		Tyrosinase , Antibacterial , AMPK
	Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.		Tyrosinase , Antibacterial , AMPK
T22464	1,2-Dimyristoyl-sn-glycerol	1,2-DMG	Others , PKC
	1,2-Dimyristoyl-sn-glycerol (1,2-DMG) is able to increase AChE activity by 35-40% at concentrations of 25 micrograms/ml in the parasite S. mansoni..		Others , PKC
T3001	Honokiol	NSC 293100	ERK , HCV Protease , MEK , Akt , Autophagy
	Honokiol (NSC-293100) is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.		ERK , HCV Protease , MEK , Akt , Autophagy
T6680	Staurosporine	Antibiotic AM-2282,AM-2282,CGP 41251	Apoptosis , PKA , Antibacterial , Antibiotic , Src , PKC , Antifungal
	Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-Fgr, phosphorylase kinase and TAOK2. Staurosporine also induces...
TQ0198	Phorbol 12-myristate 13-acetate	PMA	NF-κB , S1P Receptor , PKC
	Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB. Phorbol 12-myristate 13-acetate induces THP1 cell differentiation.		NF-κB , S1P Receptor , PKC
TN1136	Procyanidin A1	Proanthocyanidin A1	LDL , Calcium Channel , PKC
	Procyanidin A1 (Proanthocyanidin A1) has antiallergic effects, it inhibits degranulation downstream of protein kinase C activation or Ca2+; influx from an internal store in RBL-2H3 cells.		LDL , Calcium Channel , PKC
T3375	Verbascoside	Kusaginin,Acteoside,TJC160	Apoptosis , PARP , Antibacterial , PKC , p53 , HSV
	Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.		Apoptosis , PARP , Antibacterial , PKC , p53 , HSV
T3S1416	Decursin	Decursinol angelate,(+)-Decursin	Apoptosis , PKC
	1. Decursin (Decursinol angelate) is able to attenuate kainic acid-induced seizures and could have potential as an antiepileptic drug. 2. Decursin exhibits hepatoprotective effects , potentially by inhibiting the TGF-β1 ...		Apoptosis , PKC
T7792	Hispidin		Endogenous Metabolite , PKC
	Hispidin is a polyphenol originally, including antioxidant, anti-inflammatory, and cytoprotective properties		Endogenous Metabolite , PKC
T0392	Artemisinin	Qinghaosu,Artemisinine,Qinghaosu,NSC 369397,Artemisinine	HCV Protease , Ferroptosis , Akt , Parasite
	Artemisinin (Qinghaosu) is an ancient Chinese herbal therapy for malarial fevers which has been recently found to have potent activity against many forms of malarial organisms, including chloroquine-resistant Plasmodium ...		HCV Protease , Ferroptosis , Akt , Parasite
T9605	Sangivamycin	BA-90912,NSC 65346	Nucleoside Antimetabolite/Analog , PKC
	Sangivamycin (NSC-65346) is an effective inhibitor of protein kinase C (PKC, Ki = 10 μM). Sangivamycin exhibits antiproliferative activity against a variety of human cancers.		Nucleoside Antimetabolite/Analog , PKC
T5891	D-ERYTHRO-SPHINGOSINE	trans-4-Sphingenine,erythro-C18-Sphingosine,Erythrosphingosine	Phosphatase , Endogenous Metabolite , PKC
	D-erythro-Sphingosine (trans-4-Sphingenine) is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator		Phosphatase , Endogenous Metabolite , PKC
T11665	Ionomycin calcium	SQ23377 calcium	Apoptosis , Calcium Channel , Antibacterial , Antibiotic , PKC

T16791	Rottlerin	Mallotoxin,NSC 56346,NSC 94525	CaMK , Apoptosis , Others , HIV Protease , PKA , PKC , Autophagy
	Rottlerin (NSC-56346) is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor (IC50: PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM). Rottlerin causes apoptosis via caspase...
T6S0923	Hypericin	Hypericine,Cyclosan	Apoptosis , Antiviral , Influenza Virus , Tyrosine Kinases , Antibacterial , PKC
	1. Hypericin (Cyclosan) has antineoplastic activity. 2. Hypericin has antibiotic and antiviral activities. 3. Hypericin has antidepressive activity through inhibiting monoamine oxidase enzyme. 4. Hypericin inhibits RANKL...
TN1033	Sennidin A		HCV Protease , transporter , Akt , PI3K
	Sennidin A, has two hydroxyanthraquinone-like moieties, exerts inhibition on NS3 helicase with IC50 values of 0.8 μM.		HCV Protease , transporter , Akt , PI3K
T5736	1,3-Dicaffeoylquinic acid	CYNARIN,Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1S,3R,4R,5R)-,1,3-O-Dicaffeoylquinic acid,1,5-Dicaffeoylquinic acid	Reactive Oxygen Species , Akt , PI3K
	1,3-Dicaffeoylquinic acid (CYNARIN) is a natural product. It shows antioxidant and choleretic properties and is a potential immunosuppressive agent.		Reactive Oxygen Species , Akt , PI3K
TN1034	Sennidin B		HCV Protease , transporter , Akt , PI3K
	Sennidin B stimulates glucose incorporation in rat adipocytes.		HCV Protease , transporter , Akt , PI3K
T3892	Isoacteoside	Isoverbascoside	NF-κB
	Isoacteoside has the anti-inflammatory effect, mediated by action on caspase-1, mitogen-activated protein kinases (c-Jun N-terminal kinase, p38, extracellular signal-regulated protein kinase) and nuclear factor-kappa B p...		NF-κB
T3908	10-Gingerol		Apoptosis
	10-Gingerol-induced apoptosis was accompanied by phosphorylation of the mitogen-activated protein kinase (MAPKs) family, p38 MAPK (p38), c-Jun N-terminal kinase (JNK), and extracellular signal-regulated kinase (ERK).		Apoptosis
T4037	Phorbol	4β-Phorbol,(+)-Phorbol	PKC
	Phorbol (4β-Phorbol), a plant-derived diterpene, is a tumor promoter through the activation of protein kinase C.		PKC
T5239	Cholesteryl sulfate sodium	Cholesterol 3-Sulfate Sodium Salt,Sodium Cholesteryl Sulfate	Endogenous Metabolite , PKC
	Cholesteryl sulfate sodium (Sodium Cholesteryl Sulfate) is a sterol sulfate in human plasma. Cholesteryl sulfate sodium is a component of cell membrane and has a regulatory function. Cholesteryl sulfate sodium also activ...		Endogenous Metabolite , PKC
T6S1418	Praeruptorin C		Antioxidant , Calcium Channel
	1. Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. 2. Praeruptorin C partially protects cortical neurons by inhibiting the expression of GluN2B-containing NMDA receptors ...		Antioxidant , Calcium Channel
TWS1977	Kamebakaurin	Kamebakaurine	NF-κB
	1. Kamebakaurin (Kamebakaurine) has the ability to protect the liver from APAP-induced hepatotoxicity, presumably by both inhibiting the inflammatory response and oxidative stress. 2. Kamebakaurin inhibits the expression...		NF-κB
TN1448	(-)-Bornyl acetate	L-(-)-Bornyl acetate,Bornyl acetate	p38 MAPK , NF-κB , JNK , Antifungal
	(-)-Bornyl acetate (L-(-)-Bornyl acetate) is a less active enantiomer of (+)-Bornyl acetate. (-)-Bornyl acetate isolates from hyssop oil and possesses antifungal activity. (-)-Bornyl acetate shows highly active whitening...		p38 MAPK , NF-κB , JNK , Antifungal
T7285	Ionomycin		Calcium Channel
	Ionomycin is an calcium ionophore and an antibiotic that binds calcium ions (Ca2+). It is produced by the bacterium Streptomyces conglobatus.It is used in research to raise the intracellular calcium level (Ca2+) and as ...		Calcium Channel
T3889	Platycodin D		Prostaglandin Receptor , AMPK
	Platycodin D may stimulate TNF-α synthesis or inhibit degradation of TNF-α mRNA. Platycodin D (10/30 μM) suppresses prostaglandin E2 production in rat peritoneal macrophages stimulated by the protein kinase C activator 1...		Prostaglandin Receptor , AMPK
T6S1597	Mulberroside A		TNF , Tyrosinase , Interleukin
	1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberroside A resulted in enhanced inhibition of...		TNF , Tyrosinase , Interleukin
T6S1369	Vitexin	Apigenin-8-C-glucoside	Antioxidant
	1. Vitexin has antinociceptive and antispasmodic activities. 2. Vitexin exhibits a prominent first-pass effect. 3. Vitexin has antioxidant, antimyeloperoxidase, and α-glucosidase inhibitory activities. 4. Vitexin can eit...		Antioxidant
T3877	Esculentoside A		NF-κB , COX
	Esculentoside A can suppress inflammatory responses in LPS-induced ALI through inhibition of the NF-κB and mitogen-activated protein kinase signaling pathways. Esculentoside A may be useful for the treatment of autoimmun...		NF-κB , COX
T23772	Balanol	Ophiocordin,BA1,Azepinostatin,(-)-Balanol,(3R-trans)-Balanol
	Balanol is an ATP-competitive Protein Kinase C and Protein Kinase A inhibitor.
T22723	Dihydrosphingosine		Others
	Dihydrosphingosine is a Protein kinase C inhibitor.		Others
T17198	UCN-02	7-epi-Hydroxystaurosporine	Others
	UCN-02 is a selective protein kinase C inhibitor produced by Streptomyces strain N-12 (IC50s: 62 nM and 250 nM for PKC and protein kinase A (PKA), respectively).		Others
T75565	Vanicoside A
	Vanicoside A is a protein kinase C( PKC ) inhibitor from Polygonum pensylvanicum [1] .
TN4986	Selinidin		IκB/IKK , p38 MAPK , TNF
	Selinidin decreases phosphorylation of phospholipase C-gamma1, p38 mitogen-activated protein kinase, and IkappaB-alpha upon FcepsilonRI stimulation.		IκB/IKK , p38 MAPK , TNF
TN3711	Corylifol C		ERK , EGFR , p38 MAPK , MEK
	Corylifol C and, to a lesser extent, xanthoangelol are potent protein kinase inhibitors (inhibitory concentration 50% values for epidermal growth factor receptor (EGFR): 1.1 and 4.4 × 10(-6) μg/ml, respectively).		ERK , EGFR , p38 MAPK , MEK
T16726	Rebeccamycin		Topoisomerase
	Rebeccamycin is an antitumor antibiotic+ inhibits DNA topoisomerase I. Rebeccamycin appears to exert its primary antineoplastic effect by poisoning topoisomerase I. It also has a negligible effect on protein kinase C and...		Topoisomerase
T21441	Prostratin	12-Deoxyphorbol-13-acetate
	Prostratin, a protein kinase C activator, has been shown to exhibit promising therapeutic potential against other diseases such as cancer and Alzheimer's disease. Prostratin has the potential to be useful in the treatmen...
T68802	Vibsanin A
	Vibsanin A, an activator of protein kinase C (PKC) and an inhibitor of HSP90, demonstrates anti-proliferative effects on human cancer cell lines.
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天然物製品

Decursinol angelate

TN1557

Synonym:

Target: ERK, VEGFR, PKC, JNK

Hypocrellin A

T5771

Synonym:

Target: Antibacterial, PKC, Parasite

Daphnetin

T2851

Synonym: 7,8-Dihydroxycoumarin,Daphnetol

Target: EGFR, PKA, PKC, Parasite, Autophagy

Target: MMP, Sirtuin, Endogenous Metabolite, AMPK

Daphnoretin

T4S1335

Synonym: Dephnoretin,Thymelol

Target: Influenza Virus, Caspase, PKC

Cimiracemoside C

TN1499

Synonym: Cimicifugoside M

Target: AMPK

Chelerythrine

T6S0052

Synonym: Toddalin,Broussonpapyrine,Cheleritrine

Target: Apoptosis, BCL, PKC, Autophagy

Chelerythrine chloride

T3419

Synonym:

Target: Apoptosis, BCL, PKC, Autophagy

Urolithin B

T13265

Synonym:

Target: ERK, NF-κB, Akt, Endogenous Metabolite, JNK, AMPK

Desmethylglycitein

TN1299

Synonym: 6,7,4'-Trihydroxyisoflavone

Target: PI3K, CDK, PKC

Methyl cinnamate

T5552

Synonym:

Target: Tyrosinase, Antibacterial, AMPK

1,2-Dimyristoyl-sn-glycerol

Target: ERK, HCV Protease, MEK, Akt, Autophagy

Staurosporine

T6680

Synonym: Antibiotic AM-2282,AM-2282,CGP 41251

Target: Apoptosis, PKA, Antibacterial, Antibiotic, Src, PKC, Antifungal

Phorbol 12-myristate 13-acetate

TQ0198

Synonym: PMA

Target: NF-κB, S1P Receptor, PKC

Procyanidin A1

TN1136

Synonym: Proanthocyanidin A1

Target: LDL, Calcium Channel, PKC

Verbascoside

T3375

Synonym: Kusaginin,Acteoside,TJC160

Target: Apoptosis, PARP, Antibacterial, PKC, p53, HSV

Decursin

T3S1416

Synonym: Decursinol angelate,(+)-Decursin

Target: Apoptosis, PKC

Hispidin

T7792

Synonym:

Target: Endogenous Metabolite, PKC

Artemisinin

T0392

Synonym: Qinghaosu,Artemisinine,Qinghaosu,NSC 369397,Artemisinine

Target: HCV Protease, Ferroptosis, Akt, Parasite

Sangivamycin

T9605

Synonym: BA-90912,NSC 65346

Target: Nucleoside Antimetabolite/Analog, PKC

D-ERYTHRO-SPHINGOSINE

T5891

Synonym: trans-4-Sphingenine,erythro-C18-Sphingosine,Erythrosphingosine

Target: Phosphatase, Endogenous Metabolite, PKC

Ionomycin calcium

T11665

Synonym: SQ23377 calcium

Target: Apoptosis, Calcium Channel, Antibacterial, Antibiotic, PKC

Rottlerin

T16791

Synonym: Mallotoxin,NSC 56346,NSC 94525

Target: CaMK, Apoptosis, Others, HIV Protease, PKA, PKC, Autophagy

Hypericin

T6S0923

Synonym: Hypericine,Cyclosan

Target: Apoptosis, Antiviral, Influenza Virus, Tyrosine Kinases, Antibacterial, PKC

Sennidin A

TN1033

Synonym:

Target: HCV Protease, transporter, Akt, PI3K

1,3-Dicaffeoylquinic acid

T5736

Synonym: CYNARIN,Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1S,3R,4R,5R)-,1,3-O-Dicaffeoylquinic acid,1,5-Dicaffeoylquinic acid

Target: Reactive Oxygen Species, Akt, PI3K

Sennidin B

TN1034

Synonym:

Target: HCV Protease, transporter, Akt, PI3K

Isoacteoside

T3892

Synonym: Isoverbascoside

Synonym: 4β-Phorbol,(+)-Phorbol

Target: PKC

Cholesteryl sulfate sodium

T5239

Synonym: Cholesterol 3-Sulfate Sodium Salt,Sodium Cholesteryl Sulfate

Target: Endogenous Metabolite, PKC

Praeruptorin C

T6S1418

Synonym:

Target: Antioxidant, Calcium Channel

Kamebakaurin

TWS1977

Synonym: Kamebakaurine

Target: NF-κB

(-)-Bornyl acetate

TN1448

Synonym: L-(-)-Bornyl acetate,Bornyl acetate

Target: p38 MAPK, NF-κB, JNK, Antifungal

Ionomycin

T7285

Synonym:

Target: Calcium Channel

Platycodin D

T3889

Synonym:

Target: Prostaglandin Receptor, AMPK

Mulberroside A

T6S1597

Synonym:

Target: TNF, Tyrosinase, Interleukin

Vitexin

T6S1369

Synonym: Apigenin-8-C-glucoside

Synonym: Ophiocordin,BA1,Azepinostatin,(-)-Balanol,(3R-trans)-Balanol

Synonym: 7-epi-Hydroxystaurosporine

Target: IκB/IKK, p38 MAPK, TNF

Corylifol C

TN3711

Synonym:

Target: ERK, EGFR, p38 MAPK, MEK

Rebeccamycin

T16726

Synonym:

Target: Topoisomerase

Prostratin

T21441

Synonym: 12-Deoxyphorbol-13-acetate

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-04455	PKC iota Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	Protein kinase C iota type, also known as Atypical protein kinase C-lambda/iota, aPKC-lambda/iota and PRKCI, is a cytoplasm, membrane and nucleus protein which belongs to the protein kinase superfamily, AGC Ser/Thr prote...
TMPJ-01074	PKCE Protein, Human, Recombinant (His)	Human	E. coli
	Protein Kinase C Epsilon type is a member of the serine- and threonine-specific protein kinase family that can be activated by calcium and the second messenger diacylglycerol. Protein Kinase C Epsilon contains these doma...
TMPJ-01387	PACSIN2 Protein, Human, Recombinant (His)	Human	Human Cells
	Protein Kinase C and Casein Kinase Substrate in Neurons Protein 2 (PACSIN2) is a member of the PACSIN family. PACSIN2 is localized to the plasma membrane via its coiled-coil domain. PACSIN2 is widely expressed and contai...
TMPJ-01143	MERTK/Mer Protein, Human, Recombinant (aa 1-323, His)	Human	Human Cells
	Tyrosine-protein kinase Mer (MERTK) is a single-pass type I membrane protein which belongs to the MER/AXL/TYRO3 receptor kinase family. MERTK include two fibronectin type-III domains, two Ig-like C2-type domains, and one...
TMPJ-01307	PACSIN1 Protein, Human, Recombinant (His)	Human	Human Cells
	Protein Kinase C and Casein Kinase Substrate in Neurons Protein 1 (PACSIN1) belongs to the PACSIN family. PACSIN1 contains one FCH domain and one SH3 domain. PACSIN1 is highly expressed in the brain and at lower leves in...
TMPH-02472	14-3-3 beta/alpha Protein, Mouse, Recombinant (His)	Mouse	Yeast
	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine moti...
TMPH-02471	14-3-3 beta/alpha Protein, Mouse, Recombinant (E. coli, His)	Mouse	E. coli
	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine moti...
TMPY-04389	MAP3K8 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	Mitogen-activated protein kinase kinase kinase 8, also known as Cancer Osaka thyroid oncogene, Proto-oncogene c-Cot, Serine/threonine-protein kinase cot, Tumor progression locus 2 and MAP3K8, is a cytoplasm protein that ...
TMPH-02473	14-3-3 zeta/delta Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine moti...
TMPJ-00648	EGFR vIII Protein, Human, Recombinant (His)	Human	Human Cells
	The EGFR subfamily of receptor tyrosine kinases is composed of EGFR, ErbB2, ErbB3 and ErbB4. The EGFR shares 43% - 44% aa sequence identity with the ECD of human EGFR subfamily. All these family members are type I transm...
TMPJ-01382	HSPB8 Protein, Human, Recombinant (His)	Human	E. coli
	Heat shock protein beta-8 (HSPB8) belongs to the small heat shock protein (HSP20) family. This protein can be inducted by 17-beta-estradiol, and is predominantly expressed in skeletal muscle and heat, mainly located in t...
TMPJ-00646	EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated	Human	Human Cells
	The EGFR subfamily of receptor tyrosine kinases is composed of EGFR, ErbB2, ErbB3 and ErbB4. The EGFR shares 43% - 44% aa sequence identity with the ECD of human EGFR subfamily. All these family members are type I transm...
TMPJ-00647	EGFR vIII Protein, Human, Recombinant (hFc)	Human	Human Cells
	The EGFR subfamily of receptor tyrosine kinases is composed of EGFR, ErbB2, ErbB3 and ErbB4. The EGFR shares 43% - 44% aa sequence identity with the ECD of human EGFR subfamily. All these family members are type I transm...
TMPJ-00413	HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated	Human	Human Cells
	Receptor tyrosine-protein kinase erbB-3 is an enzyme that in humans is encoded by the ERBB3 gene. This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ERBB3 belon...
TMPJ-00899	HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc)	Human	Human Cells
	Receptor tyrosine-protein kinase erbB-3 is an enzyme that in humans is encoded by the ERBB3 gene. This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ERBB3 belon...
TMPJ-00402	CD117 Protein, Human, Recombinant (hFc)	Human	Human Cells
	C-Kit/SCF R is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to ...
TMPJ-00791	HER2/ERBB2 Protein, Rat, Recombinant (E. coli, His)	Rat	E. coli
	ERBB2 belongs to the protein kinase superfamily, Tyr protein kinase family and EGF receptor subfamily. It contains a protein kinase domain. ERBB2 is widely expressed in epithelial cells, and amplification and/or overexpr...
TMPJ-01261	PPP1R14A Protein, Human, Recombinant (His)	Human	E. coli
	Protein Phosphatase 1 Regulatory Subunit 14A (PPP1R14A) belongs to the PP1 inhibitor family. PPP1R14A is mapped to chromosome 19q13.13-q13.2. PPP1R14A binds directly to protein kinase C and casein kinase I. Meantime, PPP...
TMPJ-00415	HGFR/c-Met Protein, Human, Recombinant (aa 25-932, His & Avi), Biotinylated	Human	Human Cells
	Hepatocyte growth factor receptor (HGF R) is a glycosylated receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development. HGF R is synthesized as a single chain precursor which un...
TMPY-04571	ERK2 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus-Insect Cells
	MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, diffe...
TMPY-04384	Src Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Proto-oncogene tyrosine-protein kinase SRC is a hydrophobic protein belonging to the SRC family kinase including nine members that is a family of non-receptor tyrosine kinases. SRC protein may exist in different forms: C...
TMPY-05655	c-Kit Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293
	C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the pr...
TMPY-04051	c-Kit Protein, Human, Recombinant (hFc)	Human	HEK293
	C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the pr...
TMPY-01935	c-Kit Protein, Human, Recombinant (His)	Human	HEK293
	C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the pr...
TMPY-01802	c-Kit Protein, Mouse, Recombinant (His)	Mouse	HEK293
	C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the pr...
TMPY-04572	MKK4 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus-Insect Cells
	Dual specificity mitogen-activated protein kinase kinase 4, also known as MAP kinase kinase 4, MAPKK4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, c-Jun N-terminal kinase kinase 1, JNKK, and MAP2K4, is...
TMPY-04396	C-ABL/ABL1 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cy...
TMPJ-00335	TGFBR2 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β regulates cellular processes by binding to three high-affinit...
TMPY-02361	VEGFR2/KDR Protein, Human, Recombinant (His)	Human	HEK293
	VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-02028	RON/CD136 Protein, Human, Recombinant (His)	Human	HEK293
	The tyrosine kinase receptor, macrophage-stimulating 1 receptor (MST1R), a c-met-related tyrosine kinase, also known as the Ron receptor or CD136, controls cell survival and motility programs related to invasive growth. ...
TMPY-00586	CLEC-2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	CLEC1B, also known as CLEC2, is a C-type lectin-like receptor expressed in myeloid cells and NK cells. Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 and NKG2D, ...
TMPJ-00375	HGF Protein, Human, Recombinant (His)	Human	Human Cells
	HGF, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases and contains 4 kringle domains, 1 PAN domain and 1 peptidase S1 domain. HGF is secreted as an inactive 728 amino acid (aa) single chain propepti...
TMPY-02105	SCF Protein, Mouse, Recombinant (His)	Mouse	Baculovirus-Insect Cells
	Similar to Kit ligand precursor (C-kit ligand), also known as Stem cell factor (SCF), Mast cell growth factor (MGF), or Hematopoietic growth factor KL. SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encod...
TMPY-05157	TGFBR2 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma...
TMPY-02170	SCF Protein, Human, Recombinant (aa 1-189, His)	Human	Baculovirus-Insect Cells
	Similar to Kit ligand precursor (C-kit ligand), also known as Stem cell factor (SCF), Mast cell growth factor (MGF), or Hematopoietic growth factor KL. SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encod...
TMPY-04376	PLK1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Serine / threonine-protein kinase PLK1 / PLK-1, also known as polo-like kinase 1 (PLK-1) or serine / threonine-protein kinase 13 (STPK13), Polo-like kinases (PLKs), is a family of four serine / threonine protein kinases ...
TMPY-01296	HGFR/c-Met Protein, Human, Recombinant (His)	Human	HEK293
	Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR...
TMPY-00548	HGFR/c-Met Protein, Cynomolgus, Rhesus, Recombinant (His)	Cynomolgus,Rhesus	HEK293
	Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR...
TMPY-01896	HGFR/c-Met Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR...
TMPY-01774	TREM-1 Protein, Human, Recombinant (His)	Human	HEK293
	TREM1 (triggering receptor expressed on myeloid cells) is a type I transmembrane protein with a single Ig-like domain, and is selectively expressed on blood neutrophils and a subset of monocytes. As a member of the growi...
TMPY-02219	Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)	H1N1	E. coli
	The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the N...
TMPY-04298	CDCP1 Protein, Human, Recombinant (His)	Human	HEK293
	CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, ...
TMPY-03835	CDCP1 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, ...
TMPY-04116	KRAS Protein,Human,Recombinant(G12C & Q61H, His)	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-06056	KRAS Protein, Human, Recombinant (G12D, His)	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-01888	KRAS Protein,Human, Recombinant (Q61H, His)	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-04113	KRAS Protein,Human,Recombinant(G12D & Q61H, His)	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-04411	YES1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Proto-oncogene tyrosine-protein kinase Yes, also known as Proto-oncogene c-Yes, p61-Yes and YES1, is a cytoplasm protein that belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. YES1 /...
TMPY-04434	Src Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus-Insect Cells
	Proto-oncogene tyrosine-protein kinase SRC is a hydrophobic protein belonging to the SRC family kinase including nine members that is a family of non-receptor tyrosine kinases. SRC protein may exist in different forms: C...
TMPY-02761	Rack1 Protein, Human, Recombinant (His & MBP)	Human	E. coli
	The scaffolding protein, Rack1, is a seven-WD-domain-containing protein that has been implicated in binding to integrin beta subunit cytoplasmic domains and to members of two kinase families (src and protein kinase C, PK...
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PKC iota Protein, Human, Recombinant (GST)

TMPY-04455

Species: Human

Expression System: Baculovirus-Insect Cells

PKCE Protein, Human, Recombinant (His)

TMPJ-01074

Species: Human

Expression System: E. coli

PACSIN2 Protein, Human, Recombinant (His)

TMPJ-01387

Species: Human

Expression System: Human Cells

MERTK/Mer Protein, Human, Recombinant (aa 1-323, His)

TMPJ-01143

Species: Human

Expression System: Human Cells

PACSIN1 Protein, Human, Recombinant (His)

TMPJ-01307

Species: Human

Expression System: Human Cells

14-3-3 beta/alpha Protein, Mouse, Recombinant (His)

TMPH-02472

Species: Mouse

Expression System: Yeast

14-3-3 beta/alpha Protein, Mouse, Recombinant (E. coli, His)

TMPH-02471

Species: Mouse

Expression System: E. coli

MAP3K8 Protein, Human, Recombinant (GST)

TMPY-04389

Species: Human

Expression System: Baculovirus-Insect Cells

14-3-3 zeta/delta Protein, Mouse, Recombinant (His & SUMO)

TMPH-02473

Species: Mouse

Expression System: E. coli

EGFR vIII Protein, Human, Recombinant (His)

TMPJ-00648

Species: Human

Expression System: Human Cells

HSPB8 Protein, Human, Recombinant (His)

TMPJ-01382

Species: Human

Expression System: E. coli

EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated

TMPJ-00646

Species: Human

Expression System: Human Cells

EGFR vIII Protein, Human, Recombinant (hFc)

TMPJ-00647

Species: Human

Expression System: Human Cells

HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated

TMPJ-00413

Species: Human

Expression System: Human Cells

HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc)

TMPJ-00899

Species: Human

Expression System: Human Cells

CD117 Protein, Human, Recombinant (hFc)

TMPJ-00402

Species: Human

Expression System: Human Cells

HER2/ERBB2 Protein, Rat, Recombinant (E. coli, His)

TMPJ-00791

Species: Rat

Expression System: E. coli

PPP1R14A Protein, Human, Recombinant (His)

TMPJ-01261

Species: Human

Expression System: E. coli

HGFR/c-Met Protein, Human, Recombinant (aa 25-932, His & Avi), Biotinylated

TMPJ-00415

Species: Human

Expression System: Human Cells

ERK2 Protein, Mouse, Recombinant (His & GST)

TMPY-04571

Species: Mouse

Expression System: Baculovirus-Insect Cells

Src Protein, Human, Recombinant (His & GST)

TMPY-04384

Species: Human

Expression System: Baculovirus-Insect Cells

c-Kit Protein, Rhesus, Recombinant (hFc)

TMPY-05655

Species: Rhesus

Expression System: HEK293

c-Kit Protein, Human, Recombinant (hFc)

TMPY-04051

Species: Human

Expression System: HEK293

c-Kit Protein, Human, Recombinant (His)

TMPY-01935

Species: Human

Expression System: HEK293

c-Kit Protein, Mouse, Recombinant (His)

TMPY-01802

Species: Mouse

Expression System: HEK293

MKK4 Protein, Mouse, Recombinant (His & GST)

TMPY-04572

Species: Mouse

Expression System: Baculovirus-Insect Cells

C-ABL/ABL1 Protein, Human, Recombinant (GST)

TMPY-04396

Species: Human

Expression System: Baculovirus-Insect Cells

TGFBR2 Protein, Mouse, Recombinant (His)

TMPJ-00335

Species: Mouse

Expression System: Human Cells

VEGFR2/KDR Protein, Human, Recombinant (His)

TMPY-02361

Species: Human

Expression System: HEK293

RON/CD136 Protein, Human, Recombinant (His)

TMPY-02028

Species: Human

Expression System: HEK293

CLEC-2 Protein, Mouse, Recombinant (hFc)

TMPY-00586

Species: Mouse

Expression System: HEK293

HGF Protein, Human, Recombinant (His)

TMPJ-00375

Species: Human

Expression System: Human Cells

SCF Protein, Mouse, Recombinant (His)

TMPY-02105

Species: Mouse

Expression System: Baculovirus-Insect Cells

TGFBR2 Protein, Human, Recombinant (His)

TMPY-05157

Species: Human

Expression System: Baculovirus-Insect Cells

SCF Protein, Human, Recombinant (aa 1-189, His)

TMPY-02170

Species: Human

Expression System: Baculovirus-Insect Cells

PLK1 Protein, Human, Recombinant (His)

TMPY-04376

Species: Human

Expression System: Baculovirus-Insect Cells

HGFR/c-Met Protein, Human, Recombinant (His)

TMPY-01296

Species: Human

Expression System: HEK293

HGFR/c-Met Protein, Cynomolgus, Rhesus, Recombinant (His)

TMPY-00548

Species: Cynomolgus,Rhesus

Expression System: HEK293

HGFR/c-Met Protein, Mouse, Recombinant (His)

TMPY-01896

Species: Mouse

Expression System: HEK293

TREM-1 Protein, Human, Recombinant (His)

TMPY-01774

Species: Human

Expression System: HEK293

Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)

TMPY-02219

Species: H1N1

Expression System: E. coli

CDCP1 Protein, Human, Recombinant (His)

TMPY-04298

Species: Human

Expression System: HEK293

CDCP1 Protein, Rhesus, Recombinant (His)

TMPY-03835

Species: Rhesus

Expression System: HEK293

KRAS Protein,Human,Recombinant(G12C & Q61H, His)

TMPY-04116

Species: Human

Expression System: E. coli

KRAS Protein, Human, Recombinant (G12D, His)

TMPY-06056

Species: Human

Expression System: E. coli

KRAS Protein,Human, Recombinant (Q61H, His)

TMPY-01888

Species: Human

Expression System: E. coli

KRAS Protein,Human,Recombinant(G12D & Q61H, His)

TMPY-04113

Species: Human

Expression System: E. coli

YES1 Protein, Human, Recombinant (His & GST)

TMPY-04411

Species: Human

Expression System: Baculovirus-Insect Cells

Src Protein, Mouse, Recombinant (His & GST)

TMPY-04434

Species: Mouse

Expression System: Baculovirus-Insect Cells

Rack1 Protein, Human, Recombinant (His & MBP)

TMPY-02761

Species: Human

Expression System: E. coli

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カタログ番号	製品名
L3800	NF-κB Signaling Compound Library		740 compounds
	A unique collection of 740 compounds targeting NF-κB signaling for high throughput screening and high content screening;

ライブラリー

NF-κB Signaling Compound Library

L3800

Compounds: 740